STUDIES
SELECTED REFERENCE STUDIES FOR INGREDIENTS
Bagchi D, Bagchi M, and Stohs SJ, (1997), ‘Comparative in vitro oxygen radical scavenging ability of zinc methionine and selected zinc salts and antioxidants’, Gen Pharmacol, 28(1):85-91
Furst A., (2002), ‘Can nutrition affect chemical toxicity?’ Int J Toxicol. 2002 Sep-Oct;21(5):419-24.
Halder S, et al., (2019), ‘Cadmium level in brain correlates with memory impairment in F1 and F2 generation mice: improvement with quercetin’, Environ Sci Pollut Res Int, 26(10):9632-9639
Hodges RE, and Minich DM, (2015), ‘Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application’, J Nutr Metab, 2015:1-23
Hojyo S1, Fukada T2., (2016), ‘Roles of Zinc Signaling in the Immune System’ J Immunol Res.;2016:6762343. Epub 2016 Oct 31.
Jin X, et al., (2016), ‘Amelioration of particulate matter-induced oxidative damage by vitamin C and quercetin in human bronchial epithelial cells’, Chemosphere, 144:459-66
Levander OA, (1977), ‘Nutritional factors in relation to heavy metal toxicants.’ Fed Proc. 1977 Apr;36(5):1683-7
Li S, et al, (2015), ‘Lutein has a protective effect on hepatotoxicity induced by arsenic via Nrf2 signaling’, Biomed Res Int, 2015:315205
Liu W, et al., (2017), ‘The Influence of Quercetin on Maternal Immunity, Oxidative Stress, and Inflammation in Mice with Exposure of Fine Particulate Matter during Gestation’, Int J Environ Res Public Health, 14(6)
Maheshwari RK, et al., (2006), ‘Multiple biological activities of curcumin: a short review’, Life Sci., 78(18):2081-7
Messner DJ, et al., (2017), ‘Isolation and characterization of iron chelators from turmeric (Curcuma longa): selective metal binding by curcuminoids’, Biometals, 30(5):699-708
Nemmar A, Subramaniyan D, and Ali BH, (2012), ‘Protective effect of curcumin on pulmonary and cardiovascular effects induced by repeated exposure to diesel exhaust particles in mice’, PLoS One, 7(6):1-14
Péter S et al., (2015), “Nutritional Solutions to Reduce Risks of Negative Health Impacts of Air Pollution”, Nutrients, 7(12):10398–10416
Roberts RL1, Green J, Lewis B., (2009), ‘Lutein and zeaxanthin in eye and skin health.’ Clin Dermatol. 2009 Mar-Apr;27(2):195-201. doi: 10.1016/j.clindermatol.2008.01.011.
Rui Yan; Huiling Tian; Zhongxiu Du., (2019), ‘Quercetin protects PC-12 cells against hypoxia injury by down-regulation of miR-122’. Iranian Journal of Basic Medical Sciences, 22, 4, 2019, 3
Sharma S and Litonjua A, (2014), ‘Asthma, allergy, and responses to methyl donor supplements and nutrients’, J Allergy Clin Immunol, 133(5):1246-54
Wessels I, Maywald M, Rink L , (2017,) Zinc as a Gatekeeper of Immune Function. Nutrients. Nov 25;9(12):1286. doi: 10.3390/nu9121286. PMID: 29186856; PMCID: PMC5748737
Whyand T. et al., (2018) ‘Pollution and respiratory disease: can diet or supplements help? A review’, Respir. Res, 19:79
Zhong J, et al, (2017), ‘B vitamins attenuate the epigenetic effects of ambient fine particles in a pilot human intervention trial’, Proc Natl Acad Sci USA, 114(13):3503-3508
Zhong J, et al., (2017), ‘B-vitamin Supplementation Mitigates Effects of Fine Particles on Cardiac Autonomic Dysfunction and Inflammation: A Pilot Human Intervention Trial’, Sci Rep, 7:45322
SELECTED REFERENCE STUDIES FOR HEALTH IMPACTS
Andreau K, Leroux M and Bouharror A, (2012), “Health and Cellular Impacts of Air Pollutants: From Cytoprotection to Cytotoxicity”, Biochem Res Int., 2012:1-18
Bijnens EM, et al., (2017), ‘Telomere tracking from birth to adulthood and residential traffic exposure’, BMC Med, 15(1):205
Bose S, et al., (2018), ‘Prenatal nitrate air pollution exposure and reduced child lung function: Timing and fetal sex effects’, Environ Res, 167:591-597
Chang K, Hsu P, Lin C, et al. (2019),’ Traffic-related air pollutants increase the risk for age-related macular degeneration.’ Journal of Investigative Medicine 2019;67:1076-1081.
Choe SA, Jun YB, et al., (2018), ‘Association between ambient air pollution and pregnancy rate in women who underwent IVF.’ Hum Reprod. 2018 Jun 1;33(6):1071-1078.
Cosselman, K. E., Navas-Acien, A. & Kaufman, J. D., (2015),’Environmental factors in cardiovascular disease.’ Nat. Rev. Cardiol. 12, 627–642.
European Lung Foundation, (2019), ‘Air Pollution Speeds Up Aging of the Lungs and Increases Chronic Lung Disease Risk’, Science Daily, July 8
Evenson DP, and Wixon R, (2005), ‘Environmental toxicants cause sperm DNA fragmentation as detected by the Sperm Chromatin Structure Assay (SCSA)’, Toxicol Appl Pharmacol, 207(2 Suppl):532-7
Fuks KB et al., (2019), ‘Tropospheric Ozone and Skin Aging: Results From Two German Cohort Studies’, Environ Int, 124:139-144
Gomez-Mejiba SE, et al., (2009), ‘Inhalation of Environmental Stressors & Chronic Inflammation: Autoimmunity and Neurodegeneration’, Mutat Res., 674(1-2): 62–72
Ladd-Acosta C, (2019), ‘Epigenetic marks of prenatal air pollution exposure found in multiple tissues relevant for child health’, Environ Int, 126:363-376
Laing, Suzette et al. (2010),’Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues’, American journal of physiology. Cell physiology vol. 299,4 (2010): C736-49. doi:10.1152/ajpcell.00529.2009
Li N, et al., (2003), ‘Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage’, Environ Health Perspect, 111(4):455-60
Li Q, et al., (2018), ‘Effect of airborne particulate matter of 2.5 μm or less on preterm birth: A national birth cohort study in China’, Environ Int, 121(Pt 2):1128-1136
Liu W, Pan X, Vierkotter A, et al., (2018), ‘A Time-Series Study of the Effect of Air Pollution on Outpatient Visits for Acne Vulgaris in Beijing.’ Skin Pharmacol Physiol. 2018;31(2):107-113.
Magalhaes, S., Baumgartner, J. & Weichenthal, S., (2018), ‘Impacts of exposure to black carbon, elemental carbon, and ultrafine particles from indoor and outdoor sources on blood pressure in adults: A review of epidemiological evidence.’ Environ. Res. 161, 345–353.
Martens DS, and Nawrot TS, (2018), ‘Ageing at the level of telomeres in association to residential landscape and air pollution at home and work: a review of the current evidence’, Toxicol Lett, 298:42-52
Park SY, Byun EJ, Lee JD, Kim S, Kim HS. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts. Int J Mol Sci. 2018 Sep 12;19(9):2727.
Pedersen M, Giorgis-Allemand L, et al, (2013), ‘Ambient air pollution and low birthweight: a European cohort study (ESCAPE).’ Lancet Respir Med. 2013 Nov;1(9):695-704.
Prunicki, M. et al. (2018), ‘Exposure to NO2, CO, and PM2.5 is linked to regional DNA methylation differences in asthma.’ Clin Epigenet. 10, 2.
Shukla A, et al., (2019), ‘Air pollution associated epigenetic modifications: Transgenerational inheritance and underlying molecular mechanisms’, Sci Total Environ, 656:760-777
Sun X, et al., (2016), ‘The associations between birth weight and exposure to fine particulate matter (PM2.5) and its chemical constituents during pregnancy: A meta-analysis’, Environ Pollut, 211:38-47
Sunil VR, et al., (2013), ‘Ozone-Induced Injury and Oxidative Stress in Bronchiolar Epithelium Are Associated with Altered Pulmonary Mechanics’,Toxicol. Sci, 133(2), 309–319
Traboulsi H et al., (2017), ‘Inhaled Pollutants: The Molecular Scene Behind Respiratory and Systemic Diseases Associated With Ultrafine Particulate Matter’, Int J Mol Sci, 18:2
Valavanidis A, et al., (2013), ‘Pulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive oxygen species mechanisms’, Int J Environ Res Public Health, 10(9):3886-907